Study Rescue
Study Rescue & Imaging Core Lab Transfer
Missed read timelines, reader turnover and slow query resolution can put a trial's database lock at risk. When that happens, changing core labs can be the fastest way to get back on schedule.
Intrinsic Imaging takes over imaging studies already in progress. We move your data, align your charter and bring in experienced readers, so the transition is controlled and fully documented.
Our quality system has passed three FDA inspections with zero 483 observations and holds five BSI ISO certifications, so your rescued study stays inspection-ready.
How a Core Lab Transfer Works
Image archive transfer
We receive your existing image archive and read data, verify completeness and de-identification, and load it into our systems.
Charter harmonization
Our physicians review your imaging charter and read design, then align them so earlier and new reads remain consistent.
Reader mobilization
Subspecialty readers from our 1,000+ physician network are trained on your protocol and criteria before reads resume.
Site re-engagement
Sites receive updated acquisition guidelines and upload instructions, with support from our team through the transition.
No reader bottlenecks
Turnaround Time & Reader Redundancy
Deep reader bench
With 1,000+ credentialed physicians, reads are balanced across qualified readers, so a trial never depends on one person.
Agreed turnaround times
Standard and expedited read turnaround times are agreed with you up front and tracked throughout the study.
Discrepancy & adjudication workflows
Reader disagreements are flagged and sent to an independent adjudicator, with full traceability.
Endpoints we read
Modalities & Response Criteria Matrix
Confirm support for the criteria in your protocol. Custom and protocol-specific criteria are also available.
| Therapeutic area | Modalities | Response criteria & endpoints |
|---|---|---|
| Oncology | CT, MRI, PET/CT, bone scan | RECIST 1.1iRECISTmRECISTRANOLuganoPCWG3PERCISTChoi |
| Cardiology | Echocardiography, cardiac MRI, CT angiography, IVUS | LVEFStrain imagingPlaque volumeValvular regurgitation grading |
| Central Nervous System | MRI, amyloid & tau PET, DaT-SPECT | McDonald criteria (MS)Volumetric MRIHippocampal volumetryAmyloid/Tau PET |
| Musculoskeletal | X-ray, MRI, DXA | Sharp/van der HeijdeWORMSKellgren-LawrenceDXA T-scores |
| Gastroenterology | Endoscopy, MR enterography, histopathology | SES-CDMayo endoscopic scoreRobarts Histopathology IndexModified Baron |
| Ophthalmology | OCT, fundus photography, fluorescein angiography | Central subfield thicknessGeographic atrophy areaDR severity grading |
Is your study at risk?
Tell us where your trial stands and our team will respond within one business day.
3 FDA inspections
Zero 483 observations
5 BSI ISO certifications
9001, 13485, 22301, 27001, 27018
1,000+ physicians
Board-certified, fellowship-trained